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Relationship between the immune system and itching was investigated
The research team performed comprehensive experiments on mice to understand the biological mechanism of itching. In the ears of mice eczema In experiments using allergens that make up similar symptoms, some mice were allowed to itch freely, while itching was prevented in other groups. As a result of these experiments, it was discovered that itching triggers a complex chemical reaction chain on the skin.
Researchers, scratching behavior “Matter P” He found that an amino acid chain called the so -called release. The release of this substance triggers a number of reactions in the immune system by activating mast cells. This process results in the collection of neutrophils that cause inflammation of the skin and more itching. Senior researcher Daniel Kaplanexplains this situation by activating the mast cells in two different ways.
Interestingly, the research team discovered that it may be useful in some cases. Especially the most common cause of skin infections Staphylococcus aureus In the fight against the bacteria, it was observed that it was effective in reducing the number of bacteria. However, this positive effect is quite insignificant alongside the skin damage, especially in cases of chronic itching.
The results of the research seem to be promising for future treatment methods. Scientists aim to develop new approaches targeting receptors in mast cells in the treatment of inflammatory skin disorders such as Rosacea.
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